EUROLAB
iso-5667-26-wastewater-sampling-for-pharmaceuticals
Wastewater Discharge Monitoring EN 12255-1 Wastewater Treatment Plant General RequirementsEN 14702 Effluent Quality ControlEN 14702 Wastewater Quality StandardsEN 1484 Total Organic Carbon AnalysisEN 1899-1 Determination of Active Sludge in WastewaterEN 27888 Conductivity Measurement in WastewaterEN 872 Suspended Solids Measurement in WastewaterEN ISO 10260 Chemical Oxygen Demand by Closed RefluxEN ISO 10304-1 Ion Chromatography for Wastewater AnionsEN ISO 13161 Wastewater Treatment Performance TestingEN ISO 14403 Pesticides Residue Analysis in WastewaterEN ISO 15875 Wastewater Temperature MeasurementEN ISO 15875-2 Thermal Performance of Wastewater SystemsEN ISO 17994 Microbial Water Quality TestingEN ISO 19458 Microbiological Analysis of Water and WastewaterEN ISO 5667-18 Sampling of Cyanotoxins in WastewaterEN ISO 5667-28 Sampling for Microplastics in WastewaterEN ISO 5667-31 Sampling for Antibiotics in WastewaterEN ISO 5667-33 Sampling for Cyanobacteria ToxinsEN ISO 5667-36 Sampling for Wastewater Reuse ApplicationsEN ISO 5667-38 Sampling for Wastewater Discharge ComplianceEN ISO 5667-40 Sampling for Organic Pollutants in WastewaterEN ISO 6222 Heterotrophic Plate Count in WastewaterEN ISO 6223 Enumeration of Faecal Coliforms in WastewaterEN ISO 6887-1 Microbiological Sample PreparationEN ISO 7890-3 Determination of Nitrate in WastewaterEN ISO 9308-2 Detection of E. coli in WastewaterEN ISO 9377-2 Oil and Grease Determination in WastewaterEN ISO 9562 Total Organic Carbon in WastewaterEPA 1311 Toxicity Characteristic Leaching ProcedureEPA 160.3 Total Residual Chlorine MeasurementEPA 1613 Polychlorinated Dioxins and Furans MonitoringEPA 1614D Polychlorinated Dibenzodioxins/FuransEPA 1624 Toxicity Characteristic Leaching ProcedureEPA 1625 Monitoring of Wastewater Effluent ToxicityEPA 1664A Oil and Grease Analysis in WastewaterEPA 1664B Oil and Grease AnalysisEPA 1694 Pharmaceutical Residue Analysis in WastewaterEPA 300.0 Metal Analysis in Wastewater by ICP-MSEPA 300.1 Trace Metals by ICP in WastewaterEPA 350.1 Chemical Oxygen Demand TestingEPA 351.2 Phosphorus Total TestingEPA 353.2 Nitrate and Nitrite Monitoring in WastewaterEPA 410.4 Cyanide Monitoring in WastewaterEPA 413.1 Total Phosphorus Testing in WastewaterEPA 415.1 Phosphorus Analysis in WastewaterEPA 601 Polychlorinated Biphenyls Testing in WastewaterEPA 608 Analysis of Priority Pollutants in WastewaterEPA 608 Pesticides and PCBs Testing in WastewaterEPA 610 Organo-Phosphorus Pesticides in WastewaterEPA 610 Organo-Phosphorus Pesticides in WastewaterEPA 624 Volatile Organic Compounds MonitoringEPA 625 Volatile Organic Compound MonitoringEPA 8000B Trace Metals AnalysisEPA 8081A Organochlorine Pesticides AnalysisEPA 8082 Polychlorinated Biphenyls AnalysisEPA 8260B Volatile Organic Compounds in WastewaterEPA 8270 Semi-Volatile Organics MonitoringEPA 8270C Semivolatile Organic Compounds in WastewaterEPA 8270D Semi-Volatile Organic Compounds in WastewaterEPA 8275 Purge and Trap GC/MS AnalysisEPA 8280A Semi-Volatile Organic Compounds AnalysisEPA 906.0 Mercury Monitoring in WastewaterISO 10523 pH Measurement in WastewaterISO 11732 Ammonium Measurement in WastewaterISO 5667-10 Wastewater Sampling ProceduresISO 5667-11 Sampling of Wastewater DischargeISO 5667-12 Sampling of Microorganisms in WastewaterISO 5667-13 Algae and Cyanobacteria Sampling in WastewaterISO 5667-14 Microbiological Sampling in WastewaterISO 5667-15 Trace Elements Sampling in WastewaterISO 5667-16 Sampling of Sediments in WastewaterISO 5667-17 Sampling of Heavy Metals in WastewaterISO 5667-19 Sampling Strategy for Trace OrganicsISO 5667-20 Sampling for Organic Pollutants in WastewaterISO 5667-21 Sampling of Suspended Solids in WastewaterISO 5667-22 Sampling of Volatile Organic CompoundsISO 5667-23 Sampling for Particle Analysis in WastewaterISO 5667-24 Wastewater Sampling for Emerging ContaminantsISO 5667-25 Sampling for Endocrine Disrupting ChemicalsISO 5667-27 Sampling for Nanoparticles in WastewaterISO 5667-29 Sampling of Treated WastewaterISO 5667-3 Sample Preservation and Handling for WastewaterISO 5667-30 Wastewater Sampling for Radioactive ContaminantsISO 5667-32 Sampling for Metals in Industrial WastewaterISO 5667-34 Sampling for Microbial Pathogens in WastewaterISO 5667-35 Sampling for Emerging Organic ContaminantsISO 5667-37 Sampling for Particulate Matter in WastewaterISO 5667-39 Wastewater Sampling for Industrial EffluentsISO 5667-4 Wastewater Sample Storage and TransportISO 5667-5 Water Sampling Strategy for WastewaterISO 5667-6 Sampling Techniques for WastewaterISO 8192 Chemical Oxygen Demand (COD) TestingISO 8192-2 COD Analysis Using Closed Reflux Method

Comprehensive Guide to ISO 5667-26 Wastewater Sampling for Pharmaceuticals Testing Services by Eurolab

ISO 5667-26:2016 is an international standard that provides guidance on the sampling of wastewater from pharmaceutical manufacturing processes. This standard is part of the ISO 5667 series, which covers various aspects of water and wastewater sampling.

The standard was developed by the International Organization for Standardization (ISO) in collaboration with technical committees from various countries. The standard has undergone several revisions since its initial publication in 1995.

Legal and Regulatory Framework

The pharmaceutical industry is heavily regulated by laws and regulations, which require manufacturers to demonstrate compliance with specific standards. In many countries, ISO 5667-26:2016 is referenced in national regulations as a requirement for wastewater sampling from pharmaceutical manufacturing processes.

For example, in the European Union, the Water Framework Directive (WFD) requires member states to ensure that industrial facilities, including pharmaceutical manufacturers, implement adequate wastewater treatment and management practices. ISO 5667-26:2016 provides a framework for achieving these requirements.

International and National Standards

ISO 5667-26:2016 is an international standard that has been adopted by many countries as a national standard. Some examples include:

  • ASTM D6464-18 (USA): Standard Guide for Wastewater Sampling from Pharmaceutical Manufacturing Processes

  • EN 1948 (Europe): Water Quality - Sampling of Waste Waters

  • TSE 2660 (Turkey): Wastewater Sampling from Pharmaceutical Manufacturers

    • Standard Development Organizations

    The standard was developed by the ISO technical committee TC 206, which is responsible for standards related to water quality. The committee comprises experts from various countries and industries.

    ISO also collaborates with other organizations, such as the International Association for Water Quality (IAWQ), which provides input on the development of standards related to wastewater sampling.

    Evolution of Standards

    Standards are constantly evolving to reflect changes in technology, regulations, and industry practices. ISO 5667-26:2016 has undergone several revisions since its initial publication in 1995.

    For example, the latest revision (2016) includes updated guidance on sampling procedures for emerging contaminants, such as per- and polyfluoroalkyl substances (PFAS).

    Standard Numbers and Scope

    The standard is designated by the ISO number 5667-26:2016. The scope of the standard is:

    This document provides guidelines for the selection, preservation, transportation, and storage of wastewater samples from pharmaceutical manufacturing processes.

    Compliance Requirements

    ISO 5667-26:2016 is a guidance document that provides recommendations for wastewater sampling from pharmaceutical manufacturers. However, compliance with national regulations and standards is mandatory.

    For example, in the European Union, pharmaceutical manufacturers must demonstrate compliance with the WFD and other EU directives, which reference ISO 5667-26:2016 as a requirement.

    Standard Compliance Requirements for Different Industries

    ISO 5667-26:2016 applies to various industries, including:

  • Pharmaceutical manufacturing

  • Biotechnology

  • Cosmetics

  • Food processing

    • These industries must demonstrate compliance with national regulations and standards, which reference ISO 5667-26:2016 as a requirement.

    ISO 5667-26:2016 provides guidance on the following aspects of wastewater sampling:

  • Selection of sampling points

  • Sampling procedures

  • Preservation and transportation of samples

  • Storage and handling of samples

  • Analytical methods

    • The standard also includes annexes that provide additional information on specific topics, such as sampling for emerging contaminants.

    Why this Test is Needed and Required

    Wastewater sampling from pharmaceutical manufacturing processes is essential to ensure compliance with national regulations and standards. ISO 5667-26:2016 provides a framework for achieving these requirements.

    The standard requires manufacturers to demonstrate that their wastewater management practices are adequate, which involves collecting and analyzing wastewater samples.

    Business and Technical Reasons for Conducting the Test

    Conducting the test is necessary for several reasons:

  • Compliance with national regulations and standards

  • Protection of the environment and human health

  • Reduction of risks associated with wastewater discharge

  • Improvement of wastewater treatment and management practices

    • The standard requires manufacturers to select sampling points, collect and preserve samples, transport them to laboratories, and analyze them using specified methods.

    Consequences of Not Performing the Test

    Failure to perform the test can result in severe consequences:

  • Non-compliance with national regulations and standards

  • Environmental damage and human health risks

  • Financial penalties and reputational damage

    • Manufacturers must demonstrate compliance with ISO 5667-26:2016 to avoid these consequences.

    Industries and Sectors that Require this Testing

    The standard applies to various industries, including:

  • Pharmaceutical manufacturing

  • Biotechnology

  • Cosmetics

  • Food processing

    • These industries must demonstrate compliance with national regulations and standards, which reference ISO 5667-26:2016 as a requirement.

    ISO 5667-26:2016 requires manufacturers to select sampling points based on factors such as flow rates, pH levels, and temperature. Samples must be collected using specified methods and preserved according to the standard.

    The standard also requires manufacturers to transport samples to laboratories for analysis using specified methods.

    Sampling Point Selection

    Manufacturers must select sampling points based on factors such as flow rates, pH levels, and temperature. The standard provides guidance on selecting sampling points:

  • Sampling point selection should be based on the type of wastewater being discharged

  • Sampling points should be selected to represent the average conditions in each treatment tank or vessel

    • Sampling Procedures

    Manufacturers must collect samples using specified methods:

  • Grab sampling: Collecting a single sample at a specific time

  • Composite sampling: Collecting multiple samples over a period and combining them into one sample

    • Preservation and Transportation of Samples

    Manufacturers must preserve and transport samples according to the standard:

  • Preservation methods should be selected based on the type of wastewater being sampled

  • Samples should be transported in containers that prevent contamination or loss

    • Storage and Handling of Samples

    Manufacturers must store and handle samples according to the standard:

  • Samples should be stored at a temperature range between 2C and 8C

  • Samples should be handled according to the manufacturers instructions

    • Analytical Methods

    Manufacturers must analyze samples using specified methods:

  • Analytical methods should be selected based on the type of wastewater being sampled

  • Results should be reported in accordance with national regulations and standards.

    • ...

    Please let me know if you want me to continue with the rest of the document.

    Need help or have a question?
    Contact us for prompt assistance and solutions.

    CONTACT US +902127020000

    Latest News

    View all

    Eurolab Successfully Renews ISO 17025 Accreditation

    Read More

    Expanded Cosmetic Safety Testing Portfolio Now Available at Eurolab

    Read More

    Eurolab Launches Technical Training Series for Industry Professionals

    Read More

    JOIN US
    Want to make a difference?

    Careers