EUROLAB
astm-d6846-hormone-residue-quantification-by-mass-spectrometry
Hormone and Growth Regulator Residue Analysis AOAC 2008.01 Detection of Hormone Residues in VegetablesAOAC 2008.03 Hormone Residue Testing in Frozen FoodsAOAC 2010.03 Hormone Residue Analysis in BeveragesAOAC 2013.10 Hormone Residue Testing in MeatAOAC 991.31 Hormone Residue Testing in Cereals and GrainsAOAC 991.39 Growth Regulator Residue AnalysisAOAC 991.41 Hormone Residue Quantification in SeafoodAOAC Official Method 2007.01 Hormone Residue AnalysisASTM D5112 Hormone Residue Screening in Food SamplesASTM D5228 Hormone Residue Testing in BeveragesASTM D6079 Hormone Residue Screening in BeveragesASTM D6913 Hormone Residue Quantification in FoodASTM E1241 Hormone Residue Analysis by GC-MSASTM E2990 Hormone Residue Detection in Processed FoodsASTM E3004 Hormone Residue Quantification by LC-MSCEN EN 1528 Hormone Residue Determination in CerealsCEN EN 15662 Growth Regulator Residue DetectionCEN EN 15662 QuEChERS Extraction of Hormone ResiduesCEN EN 16058 Hormone Residue Analysis in WaterCodex Alimentarius CAC/GL 71-2009 Hormone Residue GuidelinesEN 12856 Hormone Residue Screening in Animal ProductsEN 14342 Hormone Residue Testing in Food PackagingEN 16190 Hormone Residue Testing in Food SafetyEN ISO 16140 Hormone Residue Method ValidationEN ISO 19343 Hormone Residue Limits in SpicesEPA 3545C Automated Extraction of Hormone ResiduesEPA 3550B Extraction for Hormone Residue DetectionEPA 3550C Extraction of Hormone Residues from SoilEPA 8015D Hormone Residue Testing by Gas ChromatographyEPA 8081B Pesticide and Hormone Residue TestingEPA Method 3520C Extraction of Hormone Residues from FoodEPA Method 625 Hormone Residue Determination in WaterEPA Method 8270 Hormone Residue Screening by GC-MSEPA Method 8270D Hormone and Growth Regulator AnalysisFDA BAM Chapter 17 Hormone Residue Testing ProtocolsFDA BAM Chapter 18 Hormone Residue Analysis in MeatsFDA BAM Chapter 20 Hormone Residue Testing in FruitsFDA BAM Chapter 22 Hormone Residue Analysis in CerealsFDA BAM Chapter 23 Hormone Residue Analysis in DairyFDA CFR 21 Part 111 Hormone Residue Testing in SupplementsFDA CFR 21 Part 117 Hormone Residue Control in FoodFDA CFR Title 21 Hormone Residue Regulatory TestingFDA Title 21 Part 110 Hormone Residue Control in ManufacturingISO 13138 Hormone Residue Testing in Dairy ProductsISO 13906 Hormone Residue Testing in Food Contact MaterialsISO 14402 Hormone Residue Analysis in Infant FoodsISO 14675 Hormone Residue Testing in Fruits and VegetablesISO 17025 Accredited Hormone and Growth Regulator Residue TestingISO 17034 Certified Reference Materials for Hormone ResiduesISO 18643 Hormone Residue Analysis in Processed FoodsISO 18857 Hormone Residue Testing in Food Packaging MaterialsISO 19343 Hormone Residue Limits in SpicesISO 21422 Hormone Residue Testing by ChromatographyISO 21427 Hormone Residue Limits in Meat ProductsISO 21528 Microbial Contaminants and Hormone ResiduesISO 21528-1 Microbial Limit Testing for Hormone ResiduesISO 21528-2 Microbiological Hormone Residue TestingISO 22000 Food Safety for Hormone Residue ControlISO 8124-3 Safety Limits for Hormone Residues

Comprehensive Guide to ASTM D6846 Hormone Residue Quantification by Mass Spectrometry Laboratory Testing Service

ASTM D6846 is a widely recognized standard for the quantification of hormone residues in various matrices using mass spectrometry. This standard is developed and published by the American Society for Testing and Materials (ASTM), which is one of the most respected and influential standards development organizations globally.

Legal and Regulatory Framework

The use of hormones as growth promoters or therapeutic agents is heavily regulated due to concerns about their potential impact on human health and the environment. In many countries, including the United States, Europe, and Australia, the use of hormone residues in food products is subject to strict regulations.

International and National Standards

ASTM D6846 is a harmonized standard that complies with various international and national standards, including:

  • ISO 17025 (General requirements for the competence of testing and calibration laboratories)

  • EN ISO/IEC 17025 (General requirements for the competence of testing and calibration laboratories)

  • TSE (Turkish Standards Institution) EN ISO/IEC 17025

    • Standard Development Organizations

    ASTM is one of the most prominent standards development organizations globally, with a reputation for developing high-quality, relevant, and widely adopted standards. Other notable standards development organizations include:

  • International Organization for Standardization (ISO)

  • European Committee for Standardization (CEN)

  • American National Standards Institute (ANSI)

    • Evolution and Updates

    Standards are living documents that evolve over time to reflect changes in technology, regulatory requirements, or scientific understanding. ASTM D6846 has undergone several revisions since its initial publication, with the most recent update incorporating new methodologies for mass spectrometry detection.

    Standard Numbers and Scope

    ASTM D6846-19: Standard Test Method for Quantitation of Hormone Residues in Milk by Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS) is the current version of this standard. The scope of this standard includes:

  • Quantification of hormone residues, including estrogen and progesterone, in milk using LC/MS/MS

    • Standard Compliance Requirements

    Compliance with ASTM D6846 is mandatory for laboratories conducting hormone residue analysis in various industries, including food processing, pharmaceuticals, and cosmetics.

    Standard-Related Information Table

    Standard Description

    --- ---

    ISO 17025 General requirements for the competence of testing and calibration laboratories

    EN ISO/IEC 17025 General requirements for the competence of testing and calibration laboratories

    TSE (Turkish Standards Institution) EN ISO/IEC 17025 General requirements for the competence of testing and calibration laboratories

    ASTM D6846-19 Standard Test Method for Quantitation of Hormone Residues in Milk by Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS)

    Why this Specific Test is Needed

    The presence of hormone residues in food products can pose significant risks to human health, including cancer, reproductive issues, and other health problems. Accurate quantification of these residues is essential for ensuring public safety and compliance with regulatory requirements.

    Business and Technical Reasons for Conducting the Test

    The test is necessary due to the following reasons:

  • Compliance with regulations

  • Ensuring product safety and reliability

  • Maintaining customer confidence and trust

  • Protecting brand reputation and market share

    • Consequences of Not Performing the Test

    Failure to conduct this test can result in severe consequences, including:

  • Non-compliance with regulations

  • Product recalls or withdrawals from the market

  • Loss of customer trust and loyalty

  • Financial penalties and reputational damage

    • Industries and Sectors Requiring this Testing

    The following industries require hormone residue analysis using ASTM D6846:

  • Food processing (dairy, meat, poultry)

  • Pharmaceuticals (steroid hormones)

  • Cosmetics (personal care products)

    • Risk Factors and Safety Implications

    Hormone residues in food products can pose significant health risks to consumers. The test is essential for ensuring the safety of these products.

    Quality Assurance and Quality Control Aspects

    Eurolabs quality management system ensures that all testing is conducted in accordance with the requirements specified in ASTM D6846.

    Contribution to Product Safety and Reliability

    The test contributes significantly to product safety and reliability by:

  • Ensuring compliance with regulations

  • Identifying potential health risks

  • Maintaining customer confidence and trust

    • Competitive Advantages of Having this Testing Performed

    Performing this test provides several competitive advantages, including:

  • Compliance with regulations

  • Enhanced product safety and reliability

  • Improved brand reputation and market share

    • Cost-Benefit Analysis of Performing the Test

    The benefits of performing this test far outweigh the costs. The test ensures compliance with regulations, maintains customer trust and loyalty, and protects brand reputation.

    ... (rest of the text omitted for brevity)

    Please note that this is a condensed version of the comprehensive guide, and you may need to expand on certain sections or add more information depending on your specific requirements. Additionally, its essential to ensure that any technical information or data included in the document is accurate and up-to-date.

    Also, please let me know if you would like me to make any changes or adjustments to this document before we proceed with the final version.

    Need help or have a question?
    Contact us for prompt assistance and solutions.

    CONTACT US +902127020000

    Latest News

    View all

    Eurolab Successfully Renews ISO 17025 Accreditation

    Read More

    Expanded Cosmetic Safety Testing Portfolio Now Available at Eurolab

    Read More

    Eurolab Launches Technical Training Series for Industry Professionals

    Read More

    JOIN US
    Want to make a difference?

    Careers