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en-14362-3-determination-of-carcinogenic-aromatic-amines-from-azo-colorants
Azo & Formaldehyde Testing ASTM D1331 Formaldehyde Emission Test in TextilesASTM D5035 Identification of Formaldehyde in Textile SamplesASTM D5036 Determination of Formaldehyde by Chromotropic Acid MethodASTM D5037 Formaldehyde Content Analysis Using Colorimetric MethodASTM D5154 Formaldehyde Detection in Textile Finishing AgentsASTM D5190 Formaldehyde Determination in Finished FabricsASTM D5195 Quantitative Formaldehyde Testing in Textile SamplesASTM D5196 Formaldehyde Content Analysis by Chromotropic Acid MethodASTM D5196 Formaldehyde Determination by Chromotropic AcidASTM D5197 Formaldehyde Emission Measurement by Gas ChromatographyASTM D5198 Formaldehyde Release Measurement from FabricsASTM D5237 Formaldehyde Content in Finished Textile ProductsASTM D5792 Formaldehyde Extraction and Quantification MethodsASTM D6195 Formaldehyde Determination Using Spectrophotometric MethodASTM D6340 Analysis of Formaldehyde in Textile MaterialsASTM D6545 Determination of Formaldehyde Concentration in FabricsEN 14362-1 Detection of Azo Colorants in Textiles by Extraction and SpectrophotometryEN 14362-10 Analysis of Restricted Azo Dyes in TextilesEN 14362-11 Identification of Aromatic Amines by GC-MSEN 14362-12 Testing for Banned Azo Dyes in TextilesEN 14362-13 Identification and Quantification of Aromatic AminesEN 14362-14 Testing for Restricted Azo ColorantsEN 14362-15 Identification of Aromatic Amines by Liquid ChromatographyEN 14362-16 Testing for Carcinogenic Aromatic AminesEN 14362-2 Identification of Aromatic Amines by Chromatographic TechniquesEN 14362-4 Analysis of Textile Extracts for Azo Dye ResiduesEN 14362-5 Aromatic Amines Quantification by GC-MSEN 14362-6 Testing for Restricted Azo Dyes in Textile ProductsEN 14362-7 Identification of Aromatic Amines by High-Performance Liquid ChromatographyEN 14362-8 Testing for Aromatic Amines in Textile FibersEN 14362-9 Quantitative Analysis of Carcinogenic AminesISO 14184-1 Determination of Formaldehyde in Textiles – Part 1: Free and Hydrolyzed FormaldehydeISO 14184-2 Determination of Formaldehyde Using HPLCISO 14184-3 Formaldehyde Determination by Derivatization and SpectrophotometryISO 14184-4 Formaldehyde Testing Using Spectrophotometric TechniquesISO 14184-5 Determination of Formaldehyde Content Using ChromatographyISO 14184-6 Measurement of Formaldehyde Emission from Textile ProductsISO 14184-7 Determination of Formaldehyde in Textiles Using SpectroscopyISO 14184-8 Formaldehyde Emission Testing in Textile ProductsISO 17234 Azo Dye Release in Dyed and Printed TextilesISO 17234 Determination of Azo Dyes Released from TextilesISO 17234 Extraction and Analysis of Azo Colorants by HPLCISO 17234 Extraction and Quantification of Azo Dyes in Dyed FabricsISO 17234 Extraction of Azo Dyes from Textile MaterialsISO 17234 Quantitative Azo Dye Analysis by LC-MSISO 17234 Quantitative Determination of Azo Dyes by LC-MS/MSISO 17234-2 Extraction of Azo Dyes Using Liquid ChromatographyOECD 406 Skin Sensitization Study for Azo CompoundsOECD 407 Repeated Dose Dermal Toxicity TestOECD 410 Acute Dermal Toxicity Testing of Textile ChemicalsOECD 412 Subchronic Dermal Toxicity StudyOECD 428 Skin Absorption Testing of Formaldehyde in TextilesOECD 429 Assessment of Skin Sensitization by FormaldehydeOECD 429 In Vivo Skin Sensitization TestingOECD 429 Skin Sensitization Assessment for Azo DyesOECD 429 Skin Sensitization Testing Protocols for FormaldehydeOECD 429 Skin Sensitization Tests for Textile FormaldehydeOECD 429 Testing of Formaldehyde in Textile Products for Skin SensitizationOECD TG 405 Acute Dermal Irritation/Corrosion TestingOECD TG 420 Acute Dermal Toxicity Testing for Textile ChemicalsOECD TG 428 Skin Absorption: Azo Dye Penetration TestingOECD TG 429 Skin Sensitization Testing for FormaldehydeOECD TG 431 In Vitro Skin Sensitization Tests

EN 14362-3 Determination of Carcinogenic Aromatic Amines from Azo Colorants Laboratory Testing Service Provided by Eurolab

The European Standard EN 14362-3:2016, Determination of carcinogenic aromatic amines from azo colorants - Part 3: Method using high-performance liquid chromatography with tandem mass spectrometry, is a laboratory testing standard that governs the determination of carcinogenic aromatic amines (CAAs) in textile and other products. This standard is part of the EN 14362 series, which provides methods for the analysis of azo colorants and their metabolites.

Legal and Regulatory Framework

The European Unions (EU) REACH Regulation (EC) No. 1907/2006 and its associated implementing regulations require that companies prioritize substance safety by minimizing risks to human health and the environment. The EUs Cosmetics Regulation (EC) No. 1223/2009 also requires the use of safe and effective methods for analyzing hazardous substances, including CAAs.

International and National Standards

EN 14362-3 is an international standard that has been adopted by several countries in the European region, including Germany, France, Italy, and the UK. The standard is based on international principles, such as those outlined in ISO/IEC Guide 98-3:2008 (Quantitative methods in metrology - Guide to the expression of uncertainty in measurement) and IUPAC guidelines for analytical chemistry.

Standard Development Organizations

The European Committee for Standardization (CEN) is responsible for developing and publishing EN standards, including EN 14362-3. The CEN is a non-profit organization that brings together national standards bodies from across Europe to develop voluntary technical specifications and standards.

Standards Evolution and Updates

Standards evolve over time to reflect changing technologies, scientific understanding, and regulatory requirements. EN 14362-3 was first published in 2005 and has undergone several revisions since then. The latest edition (EN 14362-3:2016) incorporates updates from the IUPAC guidelines for analytical chemistry and reflects advancements in high-performance liquid chromatography with tandem mass spectrometry (HPLC-MS/MS) technology.

Standard Numbers and Scope

The standard is designated as EN 14362-3:2016 and has the following scope:

  • Determination of carcinogenic aromatic amines from azo colorants using HPLC-MS/MS

  • Method applicable to textile products, including fabrics, garments, and other materials treated with azo colorants

    • Standard Compliance Requirements

    Compliance with EN 14362-3 is essential for companies that manufacture or import products containing azo colorants. Non-compliance can result in fines, penalties, and reputational damage.

    EN 14362-3 is a critical test for ensuring the safety of consumers and protecting the environment from hazardous substances. The standard provides a reliable method for detecting and quantifying CAAs in products.

    Why this Test is Needed

    The determination of carcinogenic aromatic amines from azo colorants using EN 14362-3 is essential because:

  • Azo colorants can release toxic chemicals, including CAAs, when exposed to light or heat

  • Exposure to CAAs has been linked to various health problems, including cancer

  • The standard provides a reliable method for detecting and quantifying CAAs in products

    • Business and Technical Reasons

    Conducting EN 14362-3 testing is necessary for several reasons:

  • Ensuring compliance with regulatory requirements

  • Protecting consumers from hazardous substances

  • Maintaining product safety and quality

  • Avoiding costly recalls, fines, or penalties

  • Enhancing reputation and brand image

    • Consequences of Not Performing this Test

    Failure to perform EN 14362-3 testing can result in:

  • Non-compliance with regulatory requirements

  • Exposure of consumers to hazardous substances

  • Damage to product safety and quality

  • Costly recalls, fines, or penalties

  • Loss of reputation and brand image

    • Industries and Sectors that Require this Testing

    EN 14362-3 testing is required for various industries and sectors, including:

  • Textile and fashion industry

  • Cosmetics and personal care industry

  • Chemical manufacturing industry

  • Food and beverage industry

  • Pharmaceutical industry

    • Risk Factors and Safety Implications

    The risk of exposure to CAAs can have serious health implications, including:

  • Cancer

  • Mutagenesis

  • Teratogenesis

  • Neurological damage

  • Immunological disorders

    • Quality Assurance and Quality Control Aspects

    Eurolabs EN 14362-3 testing service ensures that all samples are handled, analyzed, and reported in accordance with the standard. Our laboratory follows a strict quality assurance protocol to ensure accuracy, precision, and reliability.

    Testing Methodology (EN 14362-3)

    The standard describes the following testing methodology:

  • Sample preparation

  • HPLC-MS/MS analysis

  • Data evaluation and reporting

    • Standard Operating Procedure (SOP)

    Eurolabs SOP for EN 14362-3 testing ensures that all samples are analyzed in accordance with the standard. Our laboratory has developed a detailed SOP to ensure consistency, accuracy, and reliability.

    Equipment and Software

    Our laboratory is equipped with state-of-the-art HPLC-MS/MS equipment and software to perform EN 14362-3 testing. We use:

  • Waters Acquity H-Class UHPLC

  • Waters Xevo TQS MS/MS

  • MassLynx software

    • Certification and Accreditation

    Eurolab is certified to ISO 17025:2017 (General requirements for the competence of testing and calibration laboratories) and accredited by:

  • International Accreditation New Zealand (IANZ)

  • Swiss Accreditation Service (SAS)

    • Testing Services Offered by Eurolab

    Our laboratory offers EN 14362-3 testing services for various industries and sectors, including textile, cosmetics, chemical manufacturing, food and beverage, and pharmaceutical.

    Turnaround Time and Sample Preparation

    We offer a fast turnaround time of 7-10 working days for EN 14362-3 testing. Our experienced technicians will prepare your samples in accordance with the standard.

    Certification and Compliance Documents

    Eurolab provides certification and compliance documents for all EN 14362-3 test results, including:

  • Test report

  • Certificate of analysis

  • Compliance statement

    • Costs and Payment Terms

    Our pricing for EN 14362-3 testing services is competitive and transparent. We accept various payment methods, including credit cards, wire transfers, and online payment platforms.

    Conclusion

    EN 14362-3 testing is essential for ensuring the safety of consumers and protecting the environment from hazardous substances. Our laboratory offers a reliable and accurate EN 14362-3 testing service that ensures compliance with regulatory requirements. Contact us today to learn more about our testing services and schedule your samples for analysis.

    References

    1. European Committee for Standardization (CEN). (2016). EN 14362-3:2016 Determination of carcinogenic aromatic amines from azo colorants - Part 3: Method using high-performance liquid chromatography with tandem mass spectrometry.

    2. International Union of Pure and Applied Chemistry (IUPAC). (2015). Guidelines for the expression of uncertainty in measurement.

    3. European Commission. (2006). Regulation (EC) No. 1907/2006 Concerning the Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH).

    4. European Commission. (2009). Regulation (EC) No. 1223/2009 on cosmetic products.

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