EUROLAB
aoac-201104-multi-mycotoxin-testing-by-lc-msms
Mycotoxin Residue Analysis AOAC 2003.05 Multi-Mycotoxin Analysis in GrainsAOAC 2004.07 Ochratoxin A Analysis in CerealsAOAC 2005.01 Ochratoxin A Analysis in WineAOAC 2005.02 Aflatoxin Testing in MilkAOAC 2006.01 Zearalenone Testing in CerealsAOAC 2007.05 Patulin Analysis in Fruit ProductsAOAC 2007.08 Ochratoxin A in Coffee and CocoaAOAC 2008.01 Aflatoxin Analysis in MilkAOAC 2008.05 Fumonisin Testing in MaizeAOAC 2009.03 Zearalenone Testing in Animal FeedAOAC 2009.04 Fumonisin Testing in Animal FeedAOAC 2010.01 Ochratoxin A Testing in CerealsAOAC 2010.02 Fumonisin Analysis in CornAOAC 2011.02 Patulin Analysis in Fruit JuicesAOAC 2011.03 Patulin Testing in Fruit JuicesAOAC 2012.01 Aflatoxin Testing in GrainsAOAC 2012.01 Zearalenone Detection in CerealsAOAC 2013.01 Ochratoxin A Detection in CoffeeAOAC 2013.03 Zearalenone Testing in Animal FeedAOAC 2014.01 Multi-Mycotoxin Analysis in FeedAOAC 2014.01 Ochratoxin A in Spices TestingAOAC 2014.02 Multi-Mycotoxin Testing in CerealsAOAC 2015.01 Multi-Mycotoxin Testing in CerealsAOAC 2015.02 Multi-Mycotoxin Testing by LC-MS/MSAOAC 2016.01 Aflatoxin Testing in NutsAOAC 994.08 Aflatoxin Analysis in PeanutsAOAC Official Method 991.31 Mycotoxin Analysis in FoodCEN EN 14123 Determination of T-2 and HT-2 ToxinsCEN EN 14123 Mycotoxin Detection Using ELISACEN EN 14123 Mycotoxin ELISA ScreeningCEN EN 14123 T-2 and HT-2 Toxin AnalysisCEN EN 14132 Analysis of Deoxynivalenol in CerealsCEN EN 14132 Detection of DeoxynivalenolCEN EN 14132 Multi-Residue Mycotoxin DetectionCEN EN 14132 Mycotoxin Detection by LC-MS/MSCEN EN 14253 Limits for Mycotoxin ResiduesCEN EN 14253 Mycotoxin Limits and RegulationsCEN EN 14253 Regulation Limits for MycotoxinsCEN EN 14328 Determination of Mycotoxins in CerealsCEN EN 15662 Adapted QuEChERS for MycotoxinsCEN EN 15662 QuEChERS Method Adaptation for MycotoxinsCEN EN 15662 QuEChERS Method for MycotoxinsCEN EN 15681 LC-MS/MS Methods for Mycotoxin TestingCEN EN 15681 Multi-Residue Mycotoxin AnalysisCEN EN 15681 Rapid Screening for MycotoxinsCEN EN 15789 Ergot Alkaloid Detection MethodsCEN EN 15789 Ergot Alkaloid QuantificationCEN EN 15789 Methods for Ergot Alkaloid DetectionCEN EN 15789 Methods for Mycotoxin QuantificationCEN EN 15791 Determination of Fumonisins in MaizeCEN EN 15891 Analysis of Fusarium MycotoxinsCEN EN 15891 Determination of Ergot AlkaloidsCEN EN 15891 Fumonisin Detection in FoodCEN EN 15891 Fusarium Mycotoxin DetectionFDA Action Levels for Mycotoxins in FoodFDA Analytical Methods for MycotoxinsFDA BAM Chapter 19 Aflatoxin Testing ProtocolFDA Compliance for Mycotoxin LimitsFDA Compliance Guidelines for Mycotoxin ResiduesFDA Guidance for Analytical Methods in Mycotoxin TestingFDA Guidance for Mycotoxin Risk AssessmentFDA Guidance on Mycotoxin MonitoringFDA Method for Deoxynivalenol in FoodFDA Methods for Mycotoxin ExtractionFDA Mycotoxin Action Levels in FoodFDA Protocol for Patulin Testing in JuicesFDA Risk Assessment for Mycotoxin ExposureFDA Risk Management for MycotoxinsISO 13690 Sampling for Mycotoxin DetectionISO 13690 Sampling Methods for Mycotoxin AnalysisISO 14644 Cleanroom Standards for Mycotoxin LabsISO 14644-1 Cleanroom Classifications for Mycotoxin TestingISO 14644-2 Cleanroom Operation for Mycotoxin TestingISO 14686 Screening for Mycotoxins by ELISAISO 16050 Sampling Procedures for Mycotoxin TestingISO 16140 Validation of Mycotoxin Analytical MethodsISO 16140-2 Method Validation for Mycotoxin TestingISO 16140-3 Validation Protocols for Mycotoxin TestingISO 16140-4 Verification of Mycotoxin Analytical MethodsISO 16141 Performance Criteria for Mycotoxin TestingISO 17020 Inspection Procedures for Mycotoxin LabsISO 17025 Competence of Testing Labs for MycotoxinsISO 17025 Laboratory Accreditation for Mycotoxin TestingISO 17025 Quality Management for Mycotoxin LabsISO 17034 Reference Material Production for Mycotoxin TestingISO 17034 Reference Materials for Mycotoxin AnalysisISO 18400 Soil Sampling for Mycotoxin TestingISO 18593 Surface Sampling for Mycotoxin ContaminationISO 18593 Surface Sampling for MycotoxinsISO 18644 Proficiency Testing for Mycotoxin LabsISO 18644 Proficiency Testing Schemes for Mycotoxin LabsISO 21469 Mycotoxin Testing in Food Contact MaterialsISO 21527 Microbial Limits for MycotoxinsISO 21527-1 Microbiological Methods for Mycotoxin DetectionISO 21527-2 Microbiological Limits for Mycotoxins

AOAC 2011.04 Multi-Mycotoxin Testing by LC-MS/MS: Laboratory Testing Services

The AOAC 2011.04 Multi-Mycotoxin Testing by LC-MS/MS is a laboratory testing service that adheres to the standards set forth by the Association of Official Analytical Chemists (AOAC). This standard provides a framework for the analysis of multiple mycotoxins in food and feed products using Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) technology.

The AOAC 2011.04 standard is based on the principles outlined in the ISO 17025:2005 standard, which specifies the general requirements for the competence of testing and calibration laboratories. The AOAC 2011.04 standard also incorporates the requirements outlined in the ASTM E2587-09 standard, which provides guidelines for the analysis of mycotoxins in food and feed products.

The legal and regulatory framework surrounding this testing service is governed by national and international regulations, including:

  • EU Regulation (EC) No 1881/2006: Sets maximum limits for mycotoxin contamination in various foodstuffs.
  • FDA Guidance for Industry: Mycotoxins in Animal Feed: Provides guidance on the analysis of mycotoxins in animal feed products.
  • The international and national standards that apply to this specific laboratory test are:

  • ISO 17025:2005: General requirements for the competence of testing and calibration laboratories.
  • ASTM E2587-09: Standard Guide for Analysis of Mycotoxins in Food and Animal Feed.
  • AOAC 2011.04: Multi-Mycotoxin Testing by LC-MS/MS.
  • Standard development organizations, such as the ISO and ASTM, play a crucial role in developing and maintaining standards that ensure the accuracy and reliability of laboratory testing services.

    Standards evolve and get updated to reflect advances in technology, changes in regulations, and improvements in analytical methods. The AOAC 2011.04 standard was revised in 2018 to incorporate new analytical techniques and improve method sensitivity.

    Standard Numbers and Scope:

  • ISO 17025:2005: General requirements for the competence of testing and calibration laboratories.
  • Scope: Provides a framework for the evaluation of laboratory competence, including sampling, test methods, and reporting.

  • ASTM E2587-09: Standard Guide for Analysis of Mycotoxins in Food and Animal Feed.
  • Scope: Provides guidelines for the analysis of mycotoxins in food and animal feed products using various analytical techniques.

  • AOAC 2011.04: Multi-Mycotoxin Testing by LC-MS/MS.
  • Scope: Specifies the requirements for the analysis of multiple mycotoxins in food and feed products using LC-MS/MS technology.

    Standard Compliance Requirements for Different Industries:

  • Food manufacturers must comply with EU Regulation (EC) No 1881/2006, which sets maximum limits for mycotoxin contamination in various foodstuffs.
  • Animal feed manufacturers must comply with FDA Guidance for Industry: Mycotoxins in Animal Feed.
  • Regulatory agencies require laboratory testing services to adhere to the AOAC 2011.04 standard and ISO 17025:2005.
  • The AOAC 2011.04 Multi-Mycotoxin Testing by LC-MS/MS is a critical test that provides accurate and reliable results for multiple mycotoxins in food and feed products. The business and technical reasons for conducting this test are:

  • Ensures product safety and reliability
  • Complies with national and international regulations
  • Provides accurate and reliable results for multiple mycotoxins
  • Supports quality assurance and control programs
  • The consequences of not performing this test are:

  • Non-compliance with regulatory requirements
  • Inaccurate or unreliable results
  • Potential health risks to consumers
  • Economic losses due to product recalls or contamination
  • The industries that require this testing are:

  • Food manufacturers
  • Animal feed manufacturers
  • Regulatory agencies
  • Quality control and assurance programs
  • The AOAC 2011.04 Multi-Mycotoxin Testing by LC-MS/MS is conducted using a combination of sample preparation, chromatographic separation, and mass spectrometric detection. The testing equipment and instruments used are:

  • Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) system
  • Sample preparation equipment, including centrifuges, pipettes, and vortex mixers
  • The testing environment requirements are:

  • Temperature: 20C 5C
  • Humidity: 40 10
  • Lighting: Adequate lighting for sample handling and analysis
  • The analytical method used is based on the AOAC 2011.04 standard and involves the following steps:

    1. Sample preparation: Homogenize the sample, extract mycotoxins using a solvent, and concentrate the extract.

    2. Chromatographic separation: Separate the extracted mycotoxins using LC-MS/MS technology.

    3. Mass spectrometric detection: Detect the separated mycotoxins using tandem mass spectrometry.

    Persuasive Writing:

    At Company Name, we understand the importance of accurate and reliable laboratory testing services for our clients. Our AOAC 2011.04 Multi-Mycotoxin Testing by LC-MS/MS service ensures that your products meet regulatory requirements and provide a high level of quality assurance. With our state-of-the-art equipment and experienced analysts, you can trust us to deliver accurate results every time.

    Additional Information:

    For more information on the AOAC 2011.04 Multi-Mycotoxin Testing by LC-MS/MS service, please contact us at Company Email or visit our website at Company Website. We look forward to serving your laboratory testing needs.

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