EUROLAB
aoac-201902-detection-of-lactam-antibiotics-in-bovine-milk
Pesticide & Veterinary Drug Residues AOAC 2003.06 Chloramphenicol residue analysis in honeyAOAC 2004.08 Hormone residue detection in eggsAOAC 2006.03 Quantitation of residues in dairy productsAOAC 2007.01 Pesticide residue analysis in fruits and vegetables by LC-MS/MSAOAC 2008.05 Veterinary residue analysis in milk powderAOAC 2009.01 Pesticide residues in cocoa and chocolateAOAC 2010.01 Multiresidue analysis of pesticides in baby foodAOAC 2011.23 LC-MS/MS determination of sulfonamides in meatAOAC 2014.10 Tetracycline residues in fish and shellfish by ELISAAOAC 2015.06 Detection of pesticide residues in honey and bee productsAOAC 2016.04 Veterinary drug testing in poultry productsAOAC 2016.09 Veterinary drugs in seafood samplesAOAC 2017.02 Fluoroquinolone residue detection in beefAOAC 2017.09 Pesticide residues in citrus fruitsAOAC 2018.03 Veterinary drug residues in milk by LC-MS/MSAOAC 2018.09 Detection of macrolides in pork and beefAOAC 2020.04 LC-MS analysis of antiparasitics in sheep meatAOAC 2020.05 Multi-class pesticide screening in tea leavesAOAC 2021.06 Veterinary residues in dried meat productsAOAC 2022.01 Carbamate detection in vegetablesAOAC 2023.02 Veterinary drug screening in animal fatCAC/MRL 01 Maximum Residue Limits of Pesticides in Food Products TestingCodex CAC/MRL 1 Establishing pesticide MRLs in cereals and grainsCodex CXG 71-2009 Guidelines on residue monitoring programsCodex GL 56 Guidelines on Good Laboratory Practice for Pesticide Residue AnalysisCodex GL 56 Guidelines on performance criteria for methods of analysis for pesticidesCodex GL 71 Sampling for determination of pesticide residuesCodex GL 81 Good laboratory practices for pesticide residue testingCodex GL 90 Guideline levels for residues of veterinary drugs in foodCodex MRL Database Reference MRLs for pesticide-veterinary crossoverEPA 1657 Determination of pesticide metabolites in cropsEPA 3052 Determination of heavy metals in fertilizers and feed via acid digestionEPA 310.1 Herbicide detection in plant-based samplesEPA 314.1 Pesticide testing in animal urine samplesEPA 40 CFR Part 180 Analysis of Tolerances for Pesticide Chemical ResiduesEPA 5035A Sample preservation for volatile pesticide residue testingEPA 507 Pesticide analysis in drinking water and juicesEPA 535 Determination of chloroacetanilide herbicides in produceEPA 549.2 Aldicarb and related pesticide testing in plant tissueEPA 551.1 Determination of volatile pesticide residues in vegetablesEPA 6010D Trace metals in feed samples for pesticide contaminationEPA 608.3 Detection of pesticides in fat-rich animal tissuesEPA 8000C General protocols for pesticide residue identificationEPA 8081B Organochlorine pesticide detection by gas chromatographyEPA 8141B Organophosphorus pesticides in food matricesEPA 8151A Herbicide testing in soil and agricultural produceEPA 8151B LC-MS/MS testing of veterinary pesticide synergy effectsEPA 8270E Determination of semi-volatile pesticide residues in foodEPA 8321B Analysis of polar pesticides in animal tissues by HPLC-MSEPA 8325B Emerging pesticide residues in herbal medicinesEPA 8327 LC-MS analysis of pesticide degradation products in meatEPA 8330A Analysis of nitroaromatic pesticide residues in grainEU 2002/657/EC Validation of analytical methods for veterinary drug residuesEU 2005/34/EC Identification of residues in fresh meatEU 2009/128/EC Sustainable use of pesticides in food safety testingEU 2018/782 Residue control plan for animal-based food productsEU 2021/601 Monitoring of pesticide residues in organic foodEU 2022/617 Harmonization of veterinary residue testing protocolsEU 37/2010 Annex II Veterinary medicine residue validationEU 37/2010 Veterinary drug residue limits in foodstuffs of animal originEU 396/2005 Compliance Testing for Pesticide Residues in Fruits and VegetablesEU 396/2005 Harmonized limits for pesticide residues in food and feedEU 396/2005 Maximum residue limits of pesticides in agricultural products testingEU 625/2017 Compliance testing of veterinary drugs in aquacultureEU 744/2004 Residue control measures in aquacultureEU 96/23/EC Monitoring substances in live animals and animal productsEU SANTE/11813/2017 Sampling procedures for pesticide testingEU SANTE/12682/2019 Pesticide residues determination by QuEChERS methodEU SANTE/2020/12830 Confirmatory methods for residue analysisFAO/WHO Manual of Pesticide Residue Analysis in Agricultural CommoditiesISO 13395 Nitrite/nitrate detection in vegetables and fruitsISO 15662 Pesticide residue screening using modified QuEChERSISO 15952 Pesticide residue testing in animal feedingstuffsISO 17094 Multiclass pesticide residue testing in oilseedsISO 17190 Detection of residues in fermented animal feedISO 18330 Pesticide and veterinary drug residue detection in herbsISO 18385 Measurement of pesticide residue cross-contaminationISO 1842 Analysis of pesticide residues in feed raw materialsISO 18512 Pesticide and antibiotic residues in animal dungISO 20418 Veterinary antibiotic residues in bovine serumISO 21010 Rapid screening for multi-class residues in animal tissueISO 21458 Screening of pesticide residues using multi-residue methodsISO 22855 Determination of pesticide degradation products in foodISO 22866 Determination of Spray Drift in Field Conditions for Pesticide ApplicationISO 22892 Analysis of persistent organic pollutants in livestockISO 23161 Screening of veterinary drug residues in eggsISO 23690 Determination of pesticide metabolites in animal feedISO 24662 Pesticide residue analysis in dried plant materialsISO 24687 Pesticide metabolite residue determination in poultryISO 25102 Multiresidue pesticide testing in spices and condimentsISO 6468 Pesticide residue analysis in water using liquid-liquid extractionJECFA Evaluation-Based Testing of Veterinary Drug Residues in Animal ProductsJECFA Pesticide residue risk evaluation for animal-derived productsJECFA Residue analysis of growth promoters in animal tissuesJECFA Residue evaluation of antibiotics in livestockJECFA Residue evaluation of veterinary drugs in cattle and poultryJECFA Residue limit setting for antimicrobials in livestockJECFA Risk assessment methodology for pesticide residue evaluationJECFA Risk-based residue evaluation for export commoditiesOECD TG 509 Residue Studies in Livestock for Veterinary Drugs DetectionSANCO/12495/2011 Method Validation for Pesticide Residue Analysis in FoodsVICH GL49 Risk Assessment Studies for Veterinary Medicinal Product Residues

AOAC 2019.02 Detection of β-lactam Antibiotics in Bovine Milk Laboratory Testing Service: A Comprehensive Guide

Standard-Related Information

The AOAC 2019.02 detection of β-lactam antibiotics in bovine milk is a laboratory testing service that adheres to the standards set by various international and national organizations. The relevant standards governing this testing service are:

  • ISO/TS 17378:2020: Standard for the Detection of β-Lactam Antibiotics in Milk

  • AOAC 2019.02: Official Method for the Detection of β-Lactam Antibiotics in Bovine Milk

  • EN ISO 12348:2018: Standard for the Determination of β-Lactam Antibiotics in Milk by Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

    • These standards outline the requirements and procedures for detecting β-lactam antibiotics in bovine milk. The legal and regulatory framework surrounding this testing service is governed by:

  • European Unions (EU) Regulation No 37/2010: Maximum residue limits (MRLs) for veterinary medicinal products

  • US FDAs Code of Federal Regulations (21 CFR 530): MRLs for veterinary drugs in milk

    • The international and national standards that apply to this specific laboratory test are:

  • International Organization for Standardization (ISO): Develops and publishes International Standards for quality management, environmental management, and other areas

  • American Society for Testing and Materials (ASTM): Develops and publishes voluntary consensus standards for a wide range of materials, products, systems, and services

  • Deutsches Institut für Normung (DIN): Publishes German national standards, including those related to laboratory testing

    • Standard development organizations like ISO, ASTM, and DIN play a crucial role in ensuring the accuracy and reliability of laboratory testing services. These organizations continuously review and update their standards to reflect the latest scientific advancements and regulatory requirements.

    Standard Requirements and Needs

    The AOAC 2019.02 detection of β-lactam antibiotics in bovine milk is necessary due to the increasing concern about antibiotic residues in food products. The consequences of not performing this test can be severe, including:

  • Contamination of milk with antibiotic residues: This can lead to consumer health risks and damage to dairy industry reputation

  • Non-compliance with regulatory requirements: Failure to detect β-lactam antibiotics can result in costly fines and penalties for dairy farms and processing plants

    • This testing service is required by various industries, including:

  • Dairy farming and processing

  • Food manufacturing and trading

  • Animal health and veterinary medicine

    • The risk factors associated with not performing this test include:

  • Consumer health risks: Exposure to antibiotic residues can cause adverse health effects in humans

  • Reputation damage: Non-compliance with regulatory requirements can harm the reputation of dairy farms and processing plants

    • Quality assurance and quality control aspects are critical in laboratory testing, including:

  • Equipment calibration and maintenance

  • Sample preparation and handling

  • Testing parameters and conditions

  • Measurement and analysis methods

    • Test Conditions and Methodology

    The AOAC 2019.02 detection of β-lactam antibiotics in bovine milk is conducted using the following equipment and instruments:

  • Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) system: For detecting β-lactam antibiotics

  • Sample preparation equipment: For processing and analyzing samples

    • The testing environment requirements include:

  • Temperature control: To maintain a stable temperature range for accurate results

  • Humidity control: To prevent sample degradation and contamination

    • The sample preparation procedures involve:

  • Sample collection: From dairy farms and processing plants

  • Sample extraction: Using appropriate solvents and techniques

  • Sample analysis: By LC-MS/MS system

    • Test Reporting and Documentation

    Test results are documented and reported in accordance with the following standards:

  • ISO 17025:2018: Standard for laboratory competence

  • AOAC 2019.02: Official Method for the Detection of β-Lactam Antibiotics in Bovine Milk

    • The report format and structure include:

  • Test results: Including detected β-lactam antibiotics and concentration levels

  • Testing parameters: Such as temperature, humidity, and instrument settings

  • Measurement and analysis methods: Used to detect β-lactam antibiotics

    • Why This Test Should Be Performed

    Performing the AOAC 2019.02 detection of β-lactam antibiotics in bovine milk provides numerous benefits, including:

  • Risk assessment and mitigation: Through accurate detection of antibiotic residues

  • Quality assurance and compliance: Ensuring regulatory requirements are met

  • Competitive advantages: By demonstrating commitment to food safety and quality

  • Consumer health protection: By preventing exposure to antibiotic residues

    • Conclusion

    The AOAC 2019.02 detection of β-lactam antibiotics in bovine milk is a critical laboratory testing service that ensures the accuracy and reliability of dairy products. This comprehensive guide highlights the importance of adhering to international and national standards, including ISO/TS 17378:2020 and AOAC 2019.02. By performing this test, dairy farms and processing plants can ensure compliance with regulatory requirements, protect consumer health, and maintain a competitive edge in the market.

    Appendix

    For further information on the AOAC 2019.02 detection of β-lactam antibiotics in bovine milk, please refer to:

  • AOAC International: For official methods and guidelines

  • ISO: For international standards and publications

  • ASTM: For voluntary consensus standards and publications

    • Need help or have a question?
    Contact us for prompt assistance and solutions.

    CONTACT US +902127020000

    Latest News

    View all

    Eurolab Successfully Renews ISO 17025 Accreditation

    Read More

    Expanded Cosmetic Safety Testing Portfolio Now Available at Eurolab

    Read More

    Eurolab Launches Technical Training Series for Industry Professionals

    Read More

    JOIN US
    Want to make a difference?

    Careers