AOAC 984.27 chromium quantification in dietary supplement testing

AOAC 984.27 Chromium Quantification in Dietary Supplement Testing: Eurolabs Laboratory Testing Service

The AOAC 984.27 chromium quantification method is a standardized test for determining the levels of chromium in dietary supplements. This method is widely recognized and accepted by regulatory agencies, industry organizations, and laboratories worldwide. The standard is developed and published by the Association of Official Analytical Chemists (AOAC), which is an international organization dedicated to promoting the development and use of analytical methods.

Legal and Regulatory Framework

The AOAC 984.27 method is governed by various national and international regulations that require chromium quantification in dietary supplements. For instance, the United States Pharmacopeia (USP) requires chromium levels to be reported in dietary supplement products. The European Commissions Regulation No. 609/2013 also mandates chromium analysis in food supplements.

International and National Standards

The AOAC 984.27 method is based on international standards such as ISO 17294-1:2008 (Determination of Chromium - Part 1: Atomic Emission Spectrometry), ASTM D6330-15 (Standard Test Method for Chromium in Water and Wastewater by Inductively Coupled Plasma Atomic Emission Spectrometry), and EN 13909:2012 (Foodstuffs - Determination of chromium content - Flame atomic absorption spectrometry).

Standard Development Organizations

The AOAC, ISO, ASTM, and EN are among the leading standard development organizations that govern laboratory testing standards. These organizations collaborate with industry stakeholders to develop and update standards, ensuring they remain relevant and effective.

Evolution of Standards

Standards evolve over time due to advancements in technology, new scientific discoveries, or changes in regulatory requirements. Eurolabs quality management system is designed to adapt to these changes, ensuring our laboratory testing services always meet the latest standards.

Standard Numbers and Scope

Some key standard numbers related to AOAC 984.27 chromium quantification are:

Standard Compliance Requirements

Dietary supplement manufacturers must comply with these standards to ensure their products meet regulatory requirements. Non-compliance can result in product recalls, reputational damage, and financial losses.

Standard-Related Information Conclusion

The AOAC 984.27 method is a widely accepted standard for chromium quantification in dietary supplements. Eurolabs laboratory testing services adhere to this standard, ensuring our clients products meet regulatory requirements and maintain customer confidence.

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Why AOAC 984.27 Chromium Quantification is Needed

Chromium levels must be accurately determined in dietary supplements due to its potential health implications. High chromium levels can cause adverse effects, such as gastrointestinal problems or allergic reactions. On the other hand, inadequate chromium levels may lead to nutritional deficiencies.

Business and Technical Reasons for Conducting AOAC 984.27 Chromium Quantification

Dietary supplement manufacturers require accurate chromium quantification for several reasons:

1. Regulatory compliance: Meeting regulatory requirements is essential for product approval and market access.

2. Quality assurance: Accurate testing ensures product quality and reliability, maintaining customer trust and confidence.

3. Safety assessment: Chromium levels must be evaluated to prevent adverse health effects.

Consequences of Not Performing AOAC 984.27 Chromium Quantification

Non-compliance with regulatory requirements can result in:

1. Product recalls

2. Reputational damage

3. Financial losses

4. Regulatory actions

Industries and Sectors that Require this Testing

Dietary supplement manufacturers, including those producing energy bars, protein powders, and other food supplements, require AOAC 984.27 chromium quantification.

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Conducting the Test: A Step-by-Step Guide

AOAC 984.27 chromium quantification involves several steps:

1. Sample preparation: Grind or homogenize dietary supplement samples to ensure representative analysis.

2. Instrument setup: Configure the atomic emission spectrometer (AES) according to manufacturer instructions and AOAC guidelines.

3. Calibration and validation: Perform calibration and validation procedures using certified reference materials (CRMs).

4. Measurement and analysis: Measure chromium levels in the sample using AES, following the established protocol.

Testing Equipment and Instruments

Eurolab uses state-of-the-art atomic emission spectrometers (AES) for accurate chromium quantification:

1. Thermo Scientific iCAP TQ ICP-MS

2. Agilent Technologies 7500ce ICP-MS

Measurement Parameters

Key measurement parameters include:

1. Wavelength: 267.8 nm (cr chromium line)

2. Slit width: 10 mm

3. Integration time: 10 s

4. Number of replicates: 3

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Test Conditions and Methodology Conclusion

AOAC 984.27 chromium quantification requires adherence to established protocols, ensuring accurate and reliable results.

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Standard Requirements and Needs Conclusion

Accurate chromium quantification in dietary supplements is essential for regulatory compliance, quality assurance, and safety assessment. Eurolabs laboratory testing services meet these requirements, providing our clients with confidence in their products safety and efficacy.

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Conclusion

AOAC 984.27 chromium quantification is a widely accepted standard for determining chromium levels in dietary supplements. Eurolabs laboratory testing services adhere to this standard, ensuring regulatory compliance, quality assurance, and customer satisfaction. Our team of experts will guide you through the process, ensuring accurate results that meet your needs.

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References

AOAC (2019). Official Methods of Analysis (OMA) 23rd Edition.

ISO (2008). ISO 17294-1:2008 Determination of Chromium - Part 1: Atomic Emission Spectrometry.

ASTM (2015). ASTM D6330-15 Standard Test Method for Chromium in Water and Wastewater by Inductively Coupled Plasma Atomic Emission Spectrometry.

EN (2012). EN 13909:2012 Foodstuffs Determination of chromium content Flame atomic absorption spectrometry.

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Appendix

AOAC 984.27 Method Details:

1. Sample preparation: Grind or homogenize dietary supplement samples.

2. Instrument setup: Configure the AES according to manufacturer instructions and AOAC guidelines.

3. Calibration and validation: Perform calibration and validation procedures using CRMs.

4. Measurement and analysis: Measure chromium levels in the sample using AES, following the established protocol.

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