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en-17521-mycotoxin-profiling-in-complex-matrices-using-lc-msms
Mycotoxin Testing AOAC 2000.02 Patulin Testing in Apple PureeAOAC 2000.03 Determination of Patulin in Apple JuiceAOAC 2000.05 Patulin Detection in Fermented BeveragesAOAC 2003.01 Testing for Deoxynivalenol in Corn-Based ProductsAOAC 2003.02 Measurement of Deoxynivalenol in Wheat FlourAOAC 2003.03 Quantitative Analysis of Mycotoxins in Animal FeedAOAC 2005.06 Determination of Fumonisins by Immunoaffinity and LCAOAC 2005.07 Quantification of Aflatoxins in Tree NutsAOAC 2005.08 Determination of Zearalenone in Animal FeedAOAC 2005.09 Determination of Zearalenone in MaizeAOAC 2007.01 Quantitative Determination of Zearalenone in CornAOAC 2008.01 Fumonisin Testing in Corn GritsAOAC 2008.02 Detection of Fumonisins in Corn Using HPLC-FLDAOAC 2008.02 Quantification of Fumonisin B1 and B2 in MaizeAOAC 2008.03 Multi-Residue Detection of Mycotoxins in Animal FeedAOAC 986.16 Testing of Total Aflatoxins in Corn Using FluorometryAOAC 991.31 Aflatoxin Screening in Feed IngredientsAOAC 991.31 Determination of Aflatoxin B1 in Peanut ButterAOAC 991.31 Testing for Total Aflatoxins in Peanuts and CornAOAC 994.08 Screening of Aflatoxins by TLCAOAC 994.09 Detection of Aflatoxins in AlmondsAOAC 998.03 Screening for Aflatoxins in Maize Using Test KitsAOAC 999.07 Detection of Aflatoxin B1 in RiceCEN/TR 16059 General Protocol for Mycotoxin Testing in Food ChainsEN 14123 Determination of Ochratoxin A in Wine by Immunoaffinity ColumnEN 15289 Determination of Ochratoxin A in Cocoa by LCEN 15662 Multimycotoxin Detection in Fruits and Vegetables Using LC-MSEN 15788 Determination of Deoxynivalenol in Baby FoodEN 15792 Detection of Mycotoxins in Tomato PureeEN 15891 Determination of Trichothecenes in Food Using LC-MSEN 15891 HT-2/T-2 Detection in Baby FoodsEN 15891 Measurement of HT-2 and T-2 Toxins in CerealsEN 15891 T-2 and HT-2 Toxin Detection in OatsEN 16571 Testing of Aflatoxin M1 in Milk Products by ELISAEN 16619 Detection of Mycotoxins in Edible OilsEN 17193 Determination of Aflatoxicol in Milk and DairyEN 17194 Determination of Citrinin in Red Yeast Rice Food SupplementsEN 17200 Determination of Mycotoxins in SpicesEN 17201 Determination of Alternaria Toxins in Tomato ProductsEN 17250 Determination of Ergot Alkaloids in Feed by LC-MSEN 17299 Testing of Modified Mycotoxins in Animal FeedEN 17461 Determination of Fusarenon-X in Cereals by LC-MSEN 17462 Rapid Testing of Citrinin in Red Fermented ProductsEN 17463 Screening of Ergot Alkaloids in GrainEU 2006/401/EC Mycotoxin Control in Import CommoditiesEU Regulation 1881/2006 Compliance Testing for Mycotoxin Levels in FoodFAO Recommended Methods for Mycotoxin Sampling and DetectionFDA BAM Chapter 19 Mycotoxins Analysis ProtocolsFDA BAM Mycotoxin Analytical Methods for Regulatory MonitoringFDA CFR 21 Part 556 Testing for Mycotoxin Tolerances in Animal FeedISO 14501 Determination of Patulin in Fruit Juices by HPLCISO 15141 Determination of Deoxynivalenol in Cereals by GC-MSISO 16050 Determination of Aflatoxin B1, B2, G1, G2 in CerealsISO 16050 Determination of Aflatoxins in Foodstuffs Using HPLCISO 16050 Testing for Aflatoxins in Herbs and SpicesISO 17375 Determination of Ochratoxin A in Roasted Coffee by HPLCISO 18787 Guidelines for Mycotoxin Sampling in GrainsISO 18856 Determination of Ochratoxin A in Foodstuffs by LC-MS/MSISO 21527 Mold Enumeration for Mycotoxin-Prone FoodsISO 21527-1 Enumeration of Yeasts and Molds for Spoilage RiskISO 24276 Guidelines for Validation of Mycotoxin Detection MethodsISO 24276 Method Validation for Zearalenone DetectionJECFA Limits-Based Mycotoxin Testing in Dried FruitsJECFA Maximum Levels of Mycotoxins in Cereal GrainsJECFA Toxicity Testing for Aflatoxin M1 in Milk

EN 17521 Mycotoxin Profiling in Complex Matrices Using LC-MS/MS: Eurolabs Laboratory Testing Service

The European Standard EN 17521, Mycotoxin profiling in complex matrices using Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS), provides a framework for the determination of mycotoxins in various food and feed matrices. Mycotoxins are toxic compounds produced by certain fungi that can contaminate agricultural products, posing significant risks to human and animal health.

International and National Standards

EN 17521 is based on the following international standards:

  • ISO 21570:2013, Microbiology of food and animal feeding stuffs -- Horizontal method for the detection and quantification of aflatoxins

  • ISO 13489:2006, Microbiology of food and animal feeding stuffs -- Determination of ochratoxin A in grains and grain-based products

    • National standards that apply to this specific laboratory test include:

  • EU Regulation (EC) No. 1881/2006, setting maximum levels for certain contaminants in foodstuffs

  • EU Regulation (EU) No. 2015/2283, amending Annex II to Regulation (EC) No. 1881/2006

    • Standard Development Organizations

    The European Committee for Standardization (CEN), International Organization for Standardization (ISO), and other standard development organizations play a crucial role in the development and revision of standards related to mycotoxin analysis.

    Evolution of Standards

    Standards evolve over time due to advances in technology, changes in regulations, or new scientific findings. Eurolabs expertise and experience ensure that our laboratory testing services stay up-to-date with the latest standards and developments.

    Specific Standard Numbers and Their Scope

    EN 17521 (2015) specifies a method for the determination of mycotoxins in complex matrices using LC-MS/MS. The standard covers:

  • Aflatoxin B1, B2, G1, and G2

  • Ochratoxin A

  • Fumonisin B1, B2, and B3

    • Standard Compliance Requirements

    EN 17521 is essential for industries involved in the production, processing, and trade of food and feed products. Compliance with this standard ensures that mycotoxins are accurately detected and quantified, minimizing risks to human and animal health.

    To ensure compliance with EN 17521, laboratories must adhere to strict quality control procedures, including:

  • Calibration and validation of instruments

  • Use of certified reference materials and internal standards

  • Regular participation in interlaboratory comparisons and proficiency testing schemes

    • Eurolabs laboratory testing services meet these requirements, ensuring that our clients receive accurate and reliable results.

    Standard-Related Information (Conclusion)

    EN 17521 provides a framework for the determination of mycotoxins in complex matrices using LC-MS/MS. Compliance with this standard is essential for industries involved in food and feed production, processing, and trade. Eurolabs expertise and experience ensure that our laboratory testing services stay up-to-date with the latest standards and developments.

    Why EN 17521 Mycotoxin Profiling in Complex Matrices Using LC-MS/MS is Needed

    Mycotoxins pose significant risks to human and animal health, contaminating agricultural products worldwide. The accurate detection and quantification of mycotoxins are essential for ensuring product safety and compliance with regulations.

    Business and Technical Reasons for Conducting EN 17521 Mycotoxin Profiling in Complex Matrices Using LC-MS/MS

    The business and technical reasons for conducting EN 17521 mycotoxin profiling include:

  • Ensuring product safety and compliance with regulations

  • Minimizing risks to human and animal health

  • Maintaining customer confidence and trust

  • Enhancing competitiveness and market positioning

  • Complying with international trade agreements and regulations

    • Consequences of Not Performing EN 17521 Mycotoxin Profiling in Complex Matrices Using LC-MS/MS

    The consequences of not performing EN 17521 mycotoxin profiling include:

  • Non-compliance with regulations, resulting in fines and penalties

  • Risk to human and animal health due to contaminated products

  • Loss of customer confidence and trust

  • Decreased competitiveness and market positioning

    • Industries and Sectors Requiring EN 17521 Mycotoxin Profiling in Complex Matrices Using LC-MS/MS

    The following industries and sectors require EN 17521 mycotoxin profiling:

  • Food processing and manufacturing

  • Feed production and trade

  • Agricultural products trading

  • Import/export businesses

    • Standard Requirements and Needs (Conclusion)

    EN 17521 mycotoxin profiling is essential for ensuring product safety, compliance with regulations, and minimizing risks to human and animal health. Eurolabs laboratory testing services meet these requirements, providing accurate and reliable results.

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