EUROLAB
iso-18856-determination-of-ochratoxin-a-in-foodstuffs-by-lc-msms
Mycotoxin Testing AOAC 2000.02 Patulin Testing in Apple PureeAOAC 2000.03 Determination of Patulin in Apple JuiceAOAC 2000.05 Patulin Detection in Fermented BeveragesAOAC 2003.01 Testing for Deoxynivalenol in Corn-Based ProductsAOAC 2003.02 Measurement of Deoxynivalenol in Wheat FlourAOAC 2003.03 Quantitative Analysis of Mycotoxins in Animal FeedAOAC 2005.06 Determination of Fumonisins by Immunoaffinity and LCAOAC 2005.07 Quantification of Aflatoxins in Tree NutsAOAC 2005.08 Determination of Zearalenone in Animal FeedAOAC 2005.09 Determination of Zearalenone in MaizeAOAC 2007.01 Quantitative Determination of Zearalenone in CornAOAC 2008.01 Fumonisin Testing in Corn GritsAOAC 2008.02 Detection of Fumonisins in Corn Using HPLC-FLDAOAC 2008.02 Quantification of Fumonisin B1 and B2 in MaizeAOAC 2008.03 Multi-Residue Detection of Mycotoxins in Animal FeedAOAC 986.16 Testing of Total Aflatoxins in Corn Using FluorometryAOAC 991.31 Aflatoxin Screening in Feed IngredientsAOAC 991.31 Determination of Aflatoxin B1 in Peanut ButterAOAC 991.31 Testing for Total Aflatoxins in Peanuts and CornAOAC 994.08 Screening of Aflatoxins by TLCAOAC 994.09 Detection of Aflatoxins in AlmondsAOAC 998.03 Screening for Aflatoxins in Maize Using Test KitsAOAC 999.07 Detection of Aflatoxin B1 in RiceCEN/TR 16059 General Protocol for Mycotoxin Testing in Food ChainsEN 14123 Determination of Ochratoxin A in Wine by Immunoaffinity ColumnEN 15289 Determination of Ochratoxin A in Cocoa by LCEN 15662 Multimycotoxin Detection in Fruits and Vegetables Using LC-MSEN 15788 Determination of Deoxynivalenol in Baby FoodEN 15792 Detection of Mycotoxins in Tomato PureeEN 15891 Determination of Trichothecenes in Food Using LC-MSEN 15891 HT-2/T-2 Detection in Baby FoodsEN 15891 Measurement of HT-2 and T-2 Toxins in CerealsEN 15891 T-2 and HT-2 Toxin Detection in OatsEN 16571 Testing of Aflatoxin M1 in Milk Products by ELISAEN 16619 Detection of Mycotoxins in Edible OilsEN 17193 Determination of Aflatoxicol in Milk and DairyEN 17194 Determination of Citrinin in Red Yeast Rice Food SupplementsEN 17200 Determination of Mycotoxins in SpicesEN 17201 Determination of Alternaria Toxins in Tomato ProductsEN 17250 Determination of Ergot Alkaloids in Feed by LC-MSEN 17299 Testing of Modified Mycotoxins in Animal FeedEN 17461 Determination of Fusarenon-X in Cereals by LC-MSEN 17462 Rapid Testing of Citrinin in Red Fermented ProductsEN 17463 Screening of Ergot Alkaloids in GrainEN 17521 Mycotoxin Profiling in Complex Matrices Using LC-MS/MSEU 2006/401/EC Mycotoxin Control in Import CommoditiesEU Regulation 1881/2006 Compliance Testing for Mycotoxin Levels in FoodFAO Recommended Methods for Mycotoxin Sampling and DetectionFDA BAM Chapter 19 Mycotoxins Analysis ProtocolsFDA BAM Mycotoxin Analytical Methods for Regulatory MonitoringFDA CFR 21 Part 556 Testing for Mycotoxin Tolerances in Animal FeedISO 14501 Determination of Patulin in Fruit Juices by HPLCISO 15141 Determination of Deoxynivalenol in Cereals by GC-MSISO 16050 Determination of Aflatoxin B1, B2, G1, G2 in CerealsISO 16050 Determination of Aflatoxins in Foodstuffs Using HPLCISO 16050 Testing for Aflatoxins in Herbs and SpicesISO 17375 Determination of Ochratoxin A in Roasted Coffee by HPLCISO 18787 Guidelines for Mycotoxin Sampling in GrainsISO 21527 Mold Enumeration for Mycotoxin-Prone FoodsISO 21527-1 Enumeration of Yeasts and Molds for Spoilage RiskISO 24276 Guidelines for Validation of Mycotoxin Detection MethodsISO 24276 Method Validation for Zearalenone DetectionJECFA Limits-Based Mycotoxin Testing in Dried FruitsJECFA Maximum Levels of Mycotoxins in Cereal GrainsJECFA Toxicity Testing for Aflatoxin M1 in Milk

Comprehensive Guide to ISO 18856 Determination of Ochratoxin A in Foodstuffs by LC-MS/MS Testing Service Provided by Eurolab

Standard-Related Information

Ochratoxin A (OTA) is a mycotoxin produced by certain species of Aspergillus and Penicillium fungi. It is a natural contaminant that can be found in various foodstuffs, including grains, nuts, coffee, and wine. The determination of OTA in foodstuffs is crucial to ensure consumer safety and compliance with regulatory requirements.

The International Organization for Standardization (ISO) has published the standard ISO 18856:2011, which provides a method for the determination of OTA in foodstuffs using Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS). This standard is widely recognized and adopted by regulatory authorities worldwide.

In addition to ISO 18856, other relevant standards include:

  • ASTM E2915:2017, Standard Practice for Determination of Ochratoxin A in Foodstuffs

  • EN 1675:2018, Methods of analysis for the determination of ochratoxin A in foodstuffs by liquid chromatography-tandem mass spectrometry (LC-MS/MS)

  • TSE ISO 18856:2011, Determination of Ochratoxin A in Foodstuffs by LC-MS/MS

    • These standards provide a framework for the analysis of OTA in foodstuffs and ensure that laboratories performing this test follow established protocols.

    Standard Requirements and Needs

    The determination of OTA in foodstuffs is required to:

  • Ensure consumer safety: OTA has been linked to various health problems, including kidney damage and immunosuppression.

  • Comply with regulatory requirements: Regulatory authorities worldwide have set maximum limits for OTA in foodstuffs.

  • Protect brand reputation: Food manufacturers must demonstrate their commitment to quality and safety by testing their products.

    • The consequences of not performing this test include:

  • Non-compliance with regulations

  • Risk of consumer harm

  • Damage to brand reputation

    • Industries that require this testing include:

  • Food manufacturing

  • Agriculture

  • Brewing

  • Wine production

    • Risk factors associated with OTA contamination include:

  • Poor storage conditions

  • Inadequate handling practices

  • Contamination during processing

    • Quality assurance and quality control measures are essential to ensure the accuracy and reliability of test results.

    Test Conditions and Methodology

    The determination of OTA in foodstuffs by LC-MS/MS involves several steps, including:

    1. Sample preparation: The sample is extracted and purified using a suitable method.

    2. Instrumentation: The sample is analyzed using an LC-MS/MS system, which consists of a liquid chromatography column and a tandem mass spectrometry detector.

    3. Testing parameters: The test is performed under controlled conditions, including temperature, humidity, and pressure.

    The measurement and analysis methods used in this test include:

  • Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

  • Quantitative analysis using internal standards

    • Calibration and validation procedures are essential to ensure the accuracy and reliability of test results. Quality control measures during testing include:

  • Sample preparation blanks

  • Calibration standards

  • Validation samples

    • Test Reporting and Documentation

    The test report includes:

  • Test method used

  • Sample description

  • Results of analysis (including limits of detection and quantitation)

  • Conclusion and recommendations

    • The reporting standard for this test is ISO 17025:2018, General requirements for the competence of testing and calibration laboratories.

    The traceability and documentation requirements for this test include:

  • Calibration records

  • Validation reports

  • Quality control procedures

    • Why This Test Should Be Performed

    Performing this test provides several benefits, including:

  • Ensuring consumer safety

  • Complying with regulatory requirements

  • Protecting brand reputation

  • Improving quality assurance and quality control

    • Risk assessment and mitigation through testing are essential to ensure consumer safety.

    Quality assurance and compliance benefits include:

  • Reduced risk of non-compliance

  • Improved product safety

  • Enhanced brand reputation

    • Competitive advantages and market positioning benefits include:

  • Distinguishing oneself from competitors

  • Demonstrating commitment to quality and safety

  • Enhancing customer confidence and trust

    • Why Eurolab Should Provide This Service

    Eurolab provides a comprehensive testing service for the determination of OTA in foodstuffs by LC-MS/MS, including:

  • State-of-the-art equipment and facilities

  • Qualified and certified personnel

  • Accreditation and certification details

  • International recognition and partnerships

    • Quality management systems and procedures ensure that test results are accurate and reliable.

    Customer service and support capabilities include:

  • Turnaround time and efficiency advantages

  • Competitive pricing

  • Expert technical support

    • Conclusion

    The determination of OTA in foodstuffs by LC-MS/MS is a critical analysis for ensuring consumer safety and complying with regulatory requirements. Eurolab provides a comprehensive testing service that meets international standards, including ISO 18856:2011. Our state-of-the-art equipment, qualified personnel, and accreditation ensure accurate and reliable test results.

    We recommend performing this test to ensure compliance with regulations, protect brand reputation, and enhance customer confidence and trust.

    Need help or have a question?
    Contact us for prompt assistance and solutions.

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